For example, if a patient is receiving chemotherapy for a tumor, as the treatment kills the tumor cells a gout attack or kidney stone can develop as a result of the breakdown of the purines from those cells.
Can chemo cause gout flare ups?
Uric acid levels can be increased by factors including decreased urate excretion (renal insufficiency, medications including diuretics) and/or increased urate production (dietary excess, obesity, ethanol, malignancy/chemotherapy). Flares may be precipitated by decreased uric acid excretion or increased production.
Does chemotherapy affect uric acid?
Treatment for leukemia, such as chemotherapy, or certain leukemias with tumors that have a rapid rate of dividing cells may lead to rapid death of cancer cells and high levels of uric acid in the body.
Is gout common with cancer?
Gout is a risk factor of cancer, particularly that of urological cancers, digestive system cancers, and lung cancer.
Is gout common after chemotherapy Related Questions
What medications can trigger gout?
Thiazide diuretic medicines, or water pills, are used to control high blood pressure (hypertension). These medicines are strongly linked to the development of gout. Many older patients who develop gout take diuretics. Other medicines can also increase uric acid level and raise the risk of developing gout.
What anticancer drug causes gout?
We report the case of a patient who began to have episodes of gout during the first and second cycles of adjuvant capecitabine for stage III colon cancer. Chemotherapy-induced gout has already been described in the context of other commonly used chemotherapeutic agents, such as paclitaxel and gemcitabine.
What is the chemo treatment for gout?
In adults, allopurinol can be used to prevent kidney stones and gout. Allopurinol can be given at the start of a course of chemotherapy. When chemotherapy medicines start to kill the cancer cells, uric acid is released from these cells which can crystallise causing damage to the kidneys.
Why did I suddenly get gout?
What causes gout? Gout is caused by a build-up of a substance called uric acid in the blood. If you produce too much uric acid or your kidneys don’t filter enough out, it can build up and cause tiny sharp crystals to form in and around joints.
What is the fastest way to get rid of gout?
Medications are often the most effective way to treat gout attacks and prevent recurrent symptom flares. However, lifestyle choices also are important, and you may want to: Choose healthier beverages. Limit alcoholic beverages and drinks sweetened with fruit sugar (fructose).
Does chemo damage your joints?
Chemotherapy, steroid medications, or hormonal therapy may cause thinning of the bones, called osteoporosis, or joint pain. Immunotherapy may cause problems in the joints or muscles. These are known as rheumatologic issues. People who are not physically active may have a higher risk of these conditions.
Can chemo affect your joints?
Chemotherapy can result in various physical side effects, including cramps and pain in the muscles (myalgia), joints (arthralgia) and bones (ostealgia). Pain may be mild and intermittent, or persistent and severe.
Why do chemo patients take allopurinol?
Allopurinol is used to prevent high uric acid levels that happen due to cancer and cancer treatment. It is given in the vein (IV) or orally (by mouth).
Who is at highest risk for gout?
Are an adult male between 30‚Äì50 years old. Are overweight. Drink alcohol. Eat a lot of foods rich in purines (especially meats and seafood) Have a family history of gout. Have had an organ transplant. Have been exposed to lead. Are Asian Pacific Islander or African American.
When should you worry about gout?
If you experience sudden, intense pain in a joint, call your doctor. Gout that goes untreated can lead to worsening pain and joint damage. Seek medical care immediately if you have a fever and a joint is hot and inflamed, which can be a sign of infection.
Can gout be life threatening?
Gout will not directly cause death, but it may lead to life threatening complications without proper treatment. According to the Arthritis Foundation, gout can increase the risk of cardiovascular problems, including heart failure, heart attack, and stroke.
What vitamins help gout?
A daily multivitamin, containing the antioxidant vitamins A, C, E, the B-complex vitamins, and trace minerals, such as magnesium, calcium, zinc and selenium. Omega-3 fatty acids, such as fish oil, to help reduce inflammation and promote general health. Cold-water fish, such as salmon or halibut, are good sources.
What fruits are good for gout?
Eat: Citrus Fruits Grapefruit, oranges, pineapples, and strawberries are all great sources of vitamin C, which lowers your uric acid levels and helps prevent gout attacks.
What is the best medication to prevent gout?
Allopurinol is used for the long-term treatment and prevention of gout. Taken regularly, it can stop attacks of gout and help prevent damage to your joints. Gout occurs in people who have high levels of urate in their blood.
Why does chemotherapy cause gout?
With high levels of uric acid in your blood, as a result of your disease, the uric acid will collect and form crystals in your kidneys. This may occur during chemotherapy, and may cause your kidneys to fail.
Can gout cause tumors?
Conclusions: This study shows that gout patients are more likely to develop most cancers, especially the urological cancers: prostate, bladder, and renal cancers.